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Growing Pains in Academic Drug Discovery

In a recent Perspective, Jonathon Baell argues that compounds published as drug leads by academic laboratories commonly contain functionality that identifies them as nonspecific “pan assay interference” compounds (PAINS). Baell’s article raises broad questions about why best practices for hit and le...

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Detalles Bibliográficos
Autor Principal: Whitty, Adrian
Formato: Artigo
Idioma:Inglês
Publicado: 2011
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667403/
https://ncbi.nlm.nih.gov/pubmed/21644825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.44
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