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Growing Pains in Academic Drug Discovery

In a recent Perspective, Jonathon Baell argues that compounds published as drug leads by academic laboratories commonly contain functionality that identifies them as nonspecific “pan assay interference” compounds (PAINS). Baell’s article raises broad questions about why best practices for hit and le...

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Detalhes bibliográficos
Autor principal: Whitty, Adrian
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667403/
https://ncbi.nlm.nih.gov/pubmed/21644825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.11.44
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