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Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts

BACKGROUND: Platelet-derived growth factor (PDGF) signalling is essential for many key cellular processes in mesenchymal cells. As there is redundancy in signalling between the five PDGF ligand isoforms and three PDGF receptor isoforms, and deletion of either of the receptors in vivo produces an emb...

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Detalhes bibliográficos
Main Authors: Donovan, Johanna, Shiwen, Xu, Norman, Jill, Abraham, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667071/
https://ncbi.nlm.nih.gov/pubmed/23663505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-6-10
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