Platelet-derived growth factor alpha and beta receptors have overlapping functional activities towards fibroblasts

BACKGROUND: Platelet-derived growth factor (PDGF) signalling is essential for many key cellular processes in mesenchymal cells. As there is redundancy in signalling between the five PDGF ligand isoforms and three PDGF receptor isoforms, and deletion of either of the receptors in vivo produces an emb...

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Bibliografske podrobnosti
Main Authors: Donovan, Johanna, Shiwen, Xu, Norman, Jill, Abraham, David
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3667071/
https://ncbi.nlm.nih.gov/pubmed/23663505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-6-10
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