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Platelet-Derived Growth Factor-β Receptor Activation Is Essential for Fibroblast and Pericyte Recruitment during Cutaneous Wound Healing

Connective tissue remodeling provides mammals with a rapid mechanism to repair wounds after injury. Inappropriate activation of this reparative process leads to scarring and fibrosis. Here, we studied the effects of platelet-derived growth factor receptor-β blockade in vivo using the platelet-derive...

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Detalhes bibliográficos
Main Authors: Rajkumar, Vineeth S., Shiwen, Xu, Bostrom, Maria, Leoni, Patricia, Muddle, John, Ivarsson, Mikael, Gerdin, Bengt, Denton, Christopher P., Bou-Gharios, George, Black, Carol M., Abraham, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762470/
https://ncbi.nlm.nih.gov/pubmed/17148686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.060196
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