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Growth factor expression in degenerated intervertebral disc tissue: An immunohistochemical analysis of transforming growth factor beta, fibroblast growth factor and platelet-derived growth factor

Degenerated intervertebral disc has lost its normal architecture, and there are changes both in the nuclear and annular parts of the disc. Changes in cell shape, especially in the annulus fibrosus, have been reported. During degeneration the cells become more rounded, chondrocyte-like, whereas in th...

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Detalhes bibliográficos
Main Authors: Tolonen, Jukka, Grönblad, Mats, Vanharanta, Heikki, Virri, Johanna, Guyer, Richard D., Rytömaa, Tapio, Karaharju, Erkki O.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489346/
https://ncbi.nlm.nih.gov/pubmed/15980999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00586-005-0930-6
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