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Adenoviral Gene Transfer Corrects the Ion Transport Defect in the Sinus Epithelia of a Porcine CF Model

Cystic fibrosis (CF) pigs spontaneously develop sinus and lung disease resembling human CF. The CF pig presents a unique opportunity to use gene transfer to test hypotheses to further understand the pathogenesis of CF sinus disease. In this study, we investigated the ion transport defect in the CF s...

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Detalhes bibliográficos
Main Authors: Potash, Andrea E, Wallen, Tanner J, Karp, Philip H, Ernst, Sarah, Moninger, Thomas O, Gansemer, Nicholas D, Stoltz, David A, Zabner, Joseph, Chang, Eugene H
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666638/
https://ncbi.nlm.nih.gov/pubmed/23511247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.49
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