Sinus Hypoplasia Precedes Sinus Infection in a Porcine Model of Cystic Fibrosis

OBJECTIVES/HYPOTHESIS: Chronic sinusitis is nearly universal in humans with cystic fibrosis (CF) and is accompanied by sinus hypoplasia (small sinuses). However, whether impaired sinus development is a primary feature of loss of the cystic fibrosis transmembrane conductance regulator (CFTR) or a sec...

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Bibliografiska uppgifter
Huvudupphovsmän: Chang, Eugene H, Pezzulo, Alejandro A, Meyerholz, David K, Potash, Andrea E, Wallen, Tanner J, Reznikov, Leah R, Sieren, Jessica C, Karp, Philip H, Ernst, Sarah, Moninger, Thomas O, Gansemer, Nicholas D, McCray, Paul B, Stoltz, David A, Welsh, Michael J, Zabner, Joseph
Materialtyp: Artigo
Språk:Inglês
Publicerad: Wiley Subscription Services, Inc., A Wiley Company 2012
Ämnen:
Allergy/Rhinology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449319/
https://ncbi.nlm.nih.gov/pubmed/22711071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.23392
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