Sinus Hypoplasia Precedes Sinus Infection in a Porcine Model of Cystic Fibrosis

OBJECTIVES/HYPOTHESIS: Chronic sinusitis is nearly universal in humans with cystic fibrosis (CF) and is accompanied by sinus hypoplasia (small sinuses). However, whether impaired sinus development is a primary feature of loss of the cystic fibrosis transmembrane conductance regulator (CFTR) or a sec...

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Main Authors: Chang, Eugene H, Pezzulo, Alejandro A, Meyerholz, David K, Potash, Andrea E, Wallen, Tanner J, Reznikov, Leah R, Sieren, Jessica C, Karp, Philip H, Ernst, Sarah, Moninger, Thomas O, Gansemer, Nicholas D, McCray, Paul B, Stoltz, David A, Welsh, Michael J, Zabner, Joseph
格式: Artigo
語言:Inglês
出版: Wiley Subscription Services, Inc., A Wiley Company 2012
主題:
Allergy/Rhinology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3449319/
https://ncbi.nlm.nih.gov/pubmed/22711071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lary.23392
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