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Dendritic cell immunotherapy combined with gemcitabine chemotherapy enhances survival in a murine model of pancreatic carcinoma

Pancreatic cancer is an extremely aggressive malignancy with a dismal prognosis. Cancer patients and tumor-bearing mice have multiple immunoregulatory subsets including regulatory T cells (Tregs) and myeloid-derived suppressor cells (MDSC) that may limit the effectiveness of anti-tumor immunotherapi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ghansah, Tomar, Vohra, Nasreen, Kinney, Kathleen, Weber, Amy, Kodumudi, Krithika, Springett, Gregory, Sarnaik, Amod A., Pilon-Thomas, Shari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666559/
https://ncbi.nlm.nih.gov/pubmed/23604104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-013-1407-9
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