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Gamma interferon mediated superinduction of B7-H1 in PTEN-deficient glioblastoma: A paradoxical mechanism of immune evasion

B7-H1 is a recently discovered immunoresistance protein that is regulated post-transcriptionally after PTEN loss in malignant glioma, a deadly form of brain tumor. Here, the impact of gamma interferon mediated activation of B7-H1 was investigated in glioblastoma patients with PTEN loss. Lymphocytes...

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Bibliografske podrobnosti
Main Authors: Han, Seunggu J., Ahn, Brian J., Waldron, James S., Yang, Isaac, Fang, Shanna, Crane, Courtney A., Pieper, Russell O., Parsa, Andrew T.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666317/
https://ncbi.nlm.nih.gov/pubmed/19875977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/WNR.0b013e32833188f7
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