Immunoreceptor Tyrosine-based Inhibitory Motif (ITIM)-mediated Inhibitory Signaling is Regulated by Sequential Phosphorylation Mediated by Distinct Nonreceptor Tyrosine Kinases: A Case Study Involving PECAM-1

The activation state of many blood and vascular cells is tightly controlled by a delicate balance between receptors that contain immunoreceptor tyrosine-based activation motifs (ITAMs) and those that contain immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Precisely how the timing of cellula...

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Hlavní autoři: Tourdot, Benjamin E., Brenner, Michelle K., Keough, Kathleen C., Holyst, Trudy, Newman, Peter J., Newman, Debra K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666314/
https://ncbi.nlm.nih.gov/pubmed/23418871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi301461t
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