Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation

Immunoreceptor tyrosine-based inhibitory motif (ITIM)–containing receptors inhibit cellular responsiveness to immunoreceptor tyrosine-based activation motif (ITAM)–linked receptors. Although tyrosine phosphorylation is central to the initiation of both inhibitory ITIM and stimulatory ITAM signaling,...

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Hlavní autoři: Paddock, Cathy, Lytle, Betsy L., Peterson, Francis C., Holyst, Trudy, Newman, Peter J., Volkman, Brian F., Newman, Debra K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2011
Témata:
Thrombosis and Hemostasis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3112045/
https://ncbi.nlm.nih.gov/pubmed/21464369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-317867
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