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Hereditary Angioedema Therapy: Kallikrein Inhibition and Bradykinin Receptor Antagonism

Current strategies for the treatment of hereditary angioedema (HAE) include targeted inhibition or antagonism of the contact system, which is dysregulated in HAE patients by a C1 esterase inhibitor deficiency. Ecallantide, a plasma kallikrein inhibitor, and icatibant, a selective bradykinin-2 recept...

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Bibliografiske detaljer
Hovedforfatter: Riedl, Marc
Format: Artigo
Sprog:Inglês
Udgivet: World Allergy Organization 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666151/
https://ncbi.nlm.nih.gov/pubmed/23282868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/1939-4551-3-S3-S34
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