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Icatibant, a New Bradykinin-Receptor Antagonist, in Hereditary Angioedema
BACKGROUND: Hereditary angioedema is characterized by recurrent attacks of angioedema of the skin, larynx, and gastrointestinal tract. Bradykinin is the key mediator of symptoms. Icatibant is a selective bradykinin B2 receptor antagonist. METHODS: In two double-blind, randomized, multicenter trials,...
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| Publicado no: | N Engl J Med |
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4662377/ https://ncbi.nlm.nih.gov/pubmed/20818888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa0906393 |
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