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Hereditary Angioedema Therapy: Kallikrein Inhibition and Bradykinin Receptor Antagonism

Current strategies for the treatment of hereditary angioedema (HAE) include targeted inhibition or antagonism of the contact system, which is dysregulated in HAE patients by a C1 esterase inhibitor deficiency. Ecallantide, a plasma kallikrein inhibitor, and icatibant, a selective bradykinin-2 recept...

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Detalhes bibliográficos
Autor principal: Riedl, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: World Allergy Organization 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666151/
https://ncbi.nlm.nih.gov/pubmed/23282868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/1939-4551-3-S3-S34
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