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Computer-Aided Approaches for Targeting HIVgp41

Virus-cell fusion is the primary means by which the human immunodeficiency virus-1 (HIV) delivers its genetic material into the human T-cell host. Fusion is mediated in large part by the viral glycoprotein 41 (gp41) which advances through four distinct conformational states: (i) native, (ii) pre-hai...

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Detalhes bibliográficos
Main Authors: Allen, William J., Rizzo, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3666032/
https://ncbi.nlm.nih.gov/pubmed/23730525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology1020311
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