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Strategies for Lead Discovery: Application of Footprint Similarity Targeting HIVgp41
A highly-conserved binding pocket on HIVgp41 is an important target for development of anti-viral inhibitors. Holden et al. (Bioorg. Med. Chem. Lett. 2012) recently reported 7 experimentally-verified leads identified through a computational screen to the gp41 pocket in conjunction with a new DOCK sc...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3913180/ https://ncbi.nlm.nih.gov/pubmed/24315195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.10.022 |
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