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Small molecule inhibitors of HIVgp41 N-heptad repeat trimer formation
Identification of mechanistically novel anti-HIV fusion inhibitors was accomplished using a computer-aided structure-based design approach with the goal of blocking the formation of the N-heptad repeat (NHR) trimer of the viral protein gp41. A virtual screening strategy that included per-residue int...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4459904/ https://ncbi.nlm.nih.gov/pubmed/26013847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.04.067 |
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