Spatiotemporal Characterization of mTOR Kinase Activity Following Kainic Acid Induced Status Epilepticus and Analysis of Rat Brain Response to Chronic Rapamycin Treatment

Mammalian target of rapamycin (mTOR) is a protein kinase that senses nutrient availability, trophic factors support, cellular energy level, cellular stress, and neurotransmitters and adjusts cellular metabolism accordingly. Adequate mTOR activity is needed for development as well as proper physiolog...

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Autors principals: Macias, Matylda, Blazejczyk, Magdalena, Kazmierska, Paulina, Caban, Bartosz, Skalecka, Agnieszka, Tarkowski, Bartosz, Rodo, Anna, Konopacki, Jan, Jaworski, Jacek
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665782/
https://ncbi.nlm.nih.gov/pubmed/23724051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064455
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