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Methodology for Labeling Proteins and Peptides with Lead-212 ((212)Pb)

INTRODUCTION: Alpha particles possess an exquisite degree of cytotoxicity when employed for targeted α–particle therapy (TAT) or radioimmunotherapy (RIT). (212)Pb, which acts as an in vivo generator of the α-emitting nuclide (212)Bi has shown great promise in pre-clinical studies when used to label...

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Detalhes bibliográficos
Main Authors: Baidoo, Kwamena E., Milenic, Diane E., Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665721/
https://ncbi.nlm.nih.gov/pubmed/23602604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nucmedbio.2013.01.010
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