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Cell Killing Mechanisms and Impact on Gene Expression by Gemcitabine and (212)Pb-Trastuzumab Treatment in a Disseminated i.p. Tumor Model

In pre-clinical studies, combination therapy with gemcitabine and targeted radioimmunotherapy (RIT) using (212)Pb-trastuzumab showed tremendous therapeutic potential in the LS-174T tumor xenograft model of disseminated intraperitoneal disease. To better understand the underlying molecular basis for...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yong, Kwon Joong, Milenic, Diane E., Baidoo, Kwamena E., Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965152/
https://ncbi.nlm.nih.gov/pubmed/27467592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159904
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