A Genetic Screen Identifies Interferon-α Effector Genes Required to Suppress Hepatitis C Virus Replication

BACKGROUND & AIMS: Hepatitis C virus (HCV) infection is a leading cause of end-stage liver disease. Interferon (IFN)-α is an important component of anti-HCV therapy; it upregulates transcription of IFN-stimulated genes (ISGs)—many of which have been investigated for their anti-viral effects. How...

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Hlavní autoři: Fusco, Dahlene N., Brisac, Cynthia, John, Sinu P., Huang, Yi-Wen, Chin, Christopher R., Xie, Tiao, Zhao, Hong, Zhang, Leiliang, Chevalier, Stephane, Wambua, Daniel, Lin, Wenyu, Peng, Lee, Chung, Raymond T., Brass, Abraham L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665646/
https://ncbi.nlm.nih.gov/pubmed/23462180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.02.026
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