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Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer
Protein Phosphatase 2A (PP2A) is an important and ubiquitously expressed serine threonine phosphatase and regulates the function by dephosphorylating many critical cellular molecules like Akt, p53, c-Myc and β-catenin. It plays a critical role in cellular processes, such as cell proliferation, signa...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3665613/ https://ncbi.nlm.nih.gov/pubmed/23454242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.02.036 |
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