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Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer

Protein Phosphatase 2A (PP2A) is an important and ubiquitously expressed serine threonine phosphatase and regulates the function by dephosphorylating many critical cellular molecules like Akt, p53, c-Myc and β-catenin. It plays a critical role in cellular processes, such as cell proliferation, signa...

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Bibliografiske detaljer
Main Authors: Seshacharyulu, Parthasarathy, Pandey, Poomy, Datta, Kaustubh, Batra, Surinder K.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665613/
https://ncbi.nlm.nih.gov/pubmed/23454242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.02.036
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