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Phosphatase: PP2A structural importance, regulation and its aberrant expression in cancer

Protein Phosphatase 2A (PP2A) is an important and ubiquitously expressed serine threonine phosphatase and regulates the function by dephosphorylating many critical cellular molecules like Akt, p53, c-Myc and β-catenin. It plays a critical role in cellular processes, such as cell proliferation, signa...

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Autors principals: Seshacharyulu, Parthasarathy, Pandey, Poomy, Datta, Kaustubh, Batra, Surinder K.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665613/
https://ncbi.nlm.nih.gov/pubmed/23454242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2013.02.036
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