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MUC4 stabilizes HER2 expression and maintains the cancer stem cell population in ovarian cancer cells

BACKGROUND: Recent evidence has suggested that the capability of cancer to grow, propagate and relapse after therapy is dependent on a small subset of the cell population within the tumor, called cancer stem cells. Therefore, this subpopulation of cells needs to be targeted with different approaches...

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Detalhes bibliográficos
Main Authors: Ponnusamy, Moorthy P, Seshacharyulu, Parthasarathy, Vaz, ArokiaPriyanka, Dey, Parama, Batra, Surinder K
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3111401/
https://ncbi.nlm.nih.gov/pubmed/21521521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-4-7
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