Foxp3(+) Regulatory T Cells Are Required for Recovery from Severe Sepsis

The role of regulatory T cells (Tregs) in bacterial sepsis remains controversial because antibody-mediated depletion experiments gave conflicting results. We employed DEREG mice (DEpletion of REGulatory T cells) and a caecal ligation and puncture model to elucidate the role of CD4(+)Foxp3(+) Tregs i...

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Detalhes bibliográficos
Main Authors: Kühlhorn, Franziska, Rath, Matthias, Schmoeckel, Katrin, Cziupka, Katharina, Nguyen, Huu Hung, Hildebrandt, Petra, Hünig, Thomas, Sparwasser, Tim, Huehn, Jochen, Pötschke, Christian, Bröker, Barbara M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665556/
https://ncbi.nlm.nih.gov/pubmed/23724126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0065109
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