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Polymicrobial sepsis and non-specific immunization induce adaptive immunosuppression to a similar degree

Sepsis is frequently complicated by a state of profound immunosuppression, in its extreme form known as immunoparalysis. We have studied the role of the adaptive immune system in the murine acute peritonitis model. To read out adaptive immunosuppression, we primed post-septic and control animals by...

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Veröffentlicht in:PLoS One
Hauptverfasser: Schmoeckel, Katrin, Mrochen, Daniel M., Hühn, Jochen, Pötschke, Christian, Bröker, Barbara M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2018
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5802895/
https://ncbi.nlm.nih.gov/pubmed/29415028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0192197
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