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A protein domain-centric approach for the comparative analysis of human and yeast phenotypically relevant mutations

BACKGROUND: The body of disease mutations with known phenotypic relevance continues to increase and is expected to do so even faster with the advent of new experimental techniques such as whole-genome sequencing coupled with disease association studies. However, genomic association studies are limit...

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Autors principals: Peterson, Thomas A, Park, DoHwan, Kann, Maricel G
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665522/
https://ncbi.nlm.nih.gov/pubmed/23819456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-S3-S5
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