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Targeting self-renewal pathways in myeloid malignancies

A fundamental property of hematopoietic stem cells (HSCs) is the ability to self-renew. This is a complex process involving multiple signal transduction cascades which control the fine balance between self-renewal and differentiation through transcriptional networks. Key activators/regulators of sel...

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Detalhes bibliográficos
Main Authors: Sands, William A, Copland, Mhairi, Wheadon, Helen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665484/
https://ncbi.nlm.nih.gov/pubmed/23675967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1478-811X-11-33
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