Synthesis of Clinical-Grade [(18)F]-Fluoroestradiol as a Surrogate PET Biomarker for the Evaluation of Estrogen Receptor-Targeting Therapeutic Drug

16α-[(18)F]-fluoroestradiol ([(18)F]FES), a steroid-based positron emission tomography (PET) tracer, has emerged as a dependable tracer for the evaluation and management of estrogen receptor-positive (ER+) breast cancer patients. We have developed a fully automatic, one-pot procedure for the synthes...

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Main Authors: Dixit, Manish, Shi, Jianfeng, Wei, Ling, Afari, George, Bhattacharyya, Sibaprasad
格式: Artigo
語言:Inglês
出版: Hindawi Publishing Corporation 2013
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3665243/
https://ncbi.nlm.nih.gov/pubmed/23762549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/278607
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