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A Novel Class of Intrinsic Proteasome Inhibitory Gene Transfer Peptides

Proteasomes are multisubunit enzymes responsible for the degradation of many cytosolic proteins. The inhibition of the proteasome has been the subject of intense interest in the development of drug therapies. We have previously demonstrated that simultaneous administration of a tripeptide aldehyde p...

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Autori principali: Martin, Molly E., Rice, Kevin G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664977/
https://ncbi.nlm.nih.gov/pubmed/18095640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc700362b
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