GWAS of cerebrospinal fluid tau levels identifies novel risk variants for Alzheimer’s disease

Cerebrospinal fluid (CSF) tau, tau phosphorylated at threonine 181 (ptau) and Aβ(42) are established biomarkers for Alzheimer’s Disease (AD), and have been used as quantitative traits for genetic analyses. We performed the largest genome-wide association study for cerebrospinal fluid (CSF) tau/ptau...

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Bibliografiset tiedot
Päätekijät: Cruchaga, Carlos, Kauwe, John S.K., Harari, Oscar, Jin, Sheng Chih, Cai, Yefei, Karch, Celeste M., Benitez, Bruno, Jeng, Amanda T., Skorupa, Tara, Carrell, David, Bertelsen, Sarah, Bailey, Matthew, McKean, David, Shulman, Joshua M., De Jager, Philip L., Chibnik, Lori, Bennett, David A., Arnold, Steve E., Harold, Denise, Sims, Rebecca, Gerrish, Amy, Williams, Julie, Van Deerlin, Vivianna M., Lee, Virginia M.-Y., Shaw, Leslie M., Trojanowski, John Q., Haines, Jonathan L., Mayeux, Richard, Pericak-Vance, Margaret A., Farrer, Lindsay A., Schellenberg, Gerard D., Peskind, Elaine R., Galasko, Douglas, Fagan, Anne M., Holtzman, David M., Morris, John C., Goate, Alison M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664945/
https://ncbi.nlm.nih.gov/pubmed/23562540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.02.026
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