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Formation and dissociation of proteasome storage granules are regulated by cytosolic pH

The 26S proteasome is the major protein degradation machinery of the cell and is regulated at many levels. One mode of regulation involves accumulation of proteasomes in proteasome storage granules (PSGs) upon glucose depletion. Using a systematic robotic screening approach in yeast, we identify tra...

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Bibliografiske detaljer
Main Authors: Peters, Lee Zeev, Hazan, Rotem, Breker, Michal, Schuldiner, Maya, Ben-Aroya, Shay
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664706/
https://ncbi.nlm.nih.gov/pubmed/23690178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201211146
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