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AMPK regulates ESCRT-dependent microautophagy of proteasomes concomitant with proteasome storage granule assembly during glucose starvation

The ubiquitin-proteasome system regulates numerous cellular processes and is central to protein homeostasis. In proliferating yeast and many mammalian cells, proteasomes are highly enriched in the nucleus. In carbon-starved yeast, proteasomes migrate to the cytoplasm and collect in proteasome storag...

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Publicat a:PLoS Genet
Autors principals: Li, Jianhui, Breker, Michal, Graham, Morven, Schuldiner, Maya, Hochstrasser, Mark
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886873/
https://ncbi.nlm.nih.gov/pubmed/31738769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008387
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