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Structural changes common to catalysis in the Tpx peroxiredoxin subfamily
Thiol peroxidases (Tpxs) are dimeric 2-Cys peroxiredoxins from bacteria that preferentially reduce alkyl hydroperoxides. Catalysis requires two conserved residues, the peroxidatic cysteine and the resolving cysteine, which are located in helix α(2) and helix α(3), respectively. The partial unravelin...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3664093/ https://ncbi.nlm.nih.gov/pubmed/19699750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.040 |
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