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Structural evidence that peroxiredoxin catalytic power is based on transition state stabilization
Peroxiredoxins (Prxs) are important peroxidases associated with both antioxidant protection and redox signaling. They use a conserved Cys residue to reduce peroxide substrates. The Prxs have a remarkably high catalytic efficiency that makes them a dominant player in cell-wide peroxide reduction, but...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941395/ https://ncbi.nlm.nih.gov/pubmed/20643143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.07.022 |
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