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Structural changes common to catalysis in the Tpx peroxiredoxin subfamily

Thiol peroxidases (Tpxs) are dimeric 2-Cys peroxiredoxins from bacteria that preferentially reduce alkyl hydroperoxides. Catalysis requires two conserved residues, the peroxidatic cysteine and the resolving cysteine, which are located in helix α(2) and helix α(3), respectively. The partial unravelin...

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Bibliografiske detaljer
Main Authors: Hall, Andrea, Sankaran, Banumathi, Poole, Leslie B., Karplus, P. Andrew
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664093/
https://ncbi.nlm.nih.gov/pubmed/19699750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.08.040
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