Epithelial-Mesenchymal Transition During Oncogenic Transformation Induced by Hexavalent Chromium Involves Reactive Oxygen Species-Dependent Mechanisms in Lung Epithelial Cells

Hexavalent Chromium [Cr(VI)] is an important human carcinogen associated with pulmonary diseases and lung cancer. Exposure to Cr(VI) induces DNA damage, cell morphological change and malignant transformation in human lung epithelial cells. Despite extensive studies, the molecular mechanisms remain e...

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Main Authors: Ding, Song-Ze, Yang, Yuxiu, Li, Xiu-Ling, Michelli-Rivera, Audrey, Han, Shuangyin, Wang, Lei, Pratheeshkumar, Poyil, Wang, Xin, Lu, Jian, Yin, Yuanqin, Budhraja, Amit, Hiltron, Andrew J.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3664092/
https://ncbi.nlm.nih.gov/pubmed/23518002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.03.006
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