NADPH Oxidase Activation Is Required in Reactive Oxygen Species Generation and Cell Transformation Induced by Hexavalent Chromium

Hexavalent chromium [Cr(VI)] is a well-known human carcinogen associated with the incidence of lung cancer. Although overproduction of reactive oxygen species (ROS) has been suggested to play a major role in its carcinogenicity, the mechanisms of Cr(VI)-induced ROS production remain unclear. In this...

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Detalhes bibliográficos
Main Authors: Wang, Xin, Son, Young-Ok, Chang, Qingshan, Sun, Lijuan, Hitron, J.Andrew, Budhraja, Amit, Zhang, Zhuo, Ke, Zunji, Chen, Fei, Luo, Jia, Shi, Xianglin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Carcinogenicity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179675/
https://ncbi.nlm.nih.gov/pubmed/21742780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr180
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