Role of ATF7-TAF12 interactions in the VDR hyper-sensitivity of osteoclast precursors in Paget’s disease

Osteoclast (OCL) precursors from many Paget's disease (PD) patients express measles virus nucleocapsid protein (MVNP) and are hypersensitive to 1,25-(OH)(2)D(3). The increased 1,25-(OH)(2)D(3) sensitivity is mediated by TAF12, a co-activator of VDR, which is present at much higher levels in MVN...

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Autori principali: Teramachi, Jumpei, Hiruma, Yuko, Ishizuka, Seiichi, Ishizuka, Hisako, Brown, Jacques P., Michou, Laëtitia, Cao, Huiling, Galson, Deborah L, Subler, Mark A, Zhou, Hua, Dempster, David W, Windle, Jolene J, Roodman, G. David, Kurihara, Noriyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663902/
https://ncbi.nlm.nih.gov/pubmed/23426901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1884
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