HIV-1 gp41 envelope IgA is frequently elicited after transmission but has an initial short response half-life

Prevention of HIV-1 transmission at mucosal surfaces will likely require durable pre-existing mucosal anti-HIV-1 antibodies (Abs). Defining the ontogeny, specificities and potentially protective nature of the initial mucosal virus-specific B-cell response will be critical for understanding how to in...

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Main Authors: Yates, N L, Stacey, A R, Nolen, T L, Vandergrift, N A, Moody, M A, Montefiori, D C, Weinhold, K J, Blattner, W A, Borrow, P, Shattock, R, Cohen, M S, Haynes, B F, Tomaras, G D
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663876/
https://ncbi.nlm.nih.gov/pubmed/23299618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mi.2012.107
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