Interferon Regulatory Factor 8-Deficiency Determines Massive Neutrophil Recruitment but T Cell Defect in Fast Growing Granulomas during Tuberculosis

Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS). Interferon regulatory factor-8 (IRF-8) plays an important role in host defense against Mtb, al...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Rocca, Stefano, Schiavoni, Giovanna, Sali, Michela, Anfossi, Antonio Giovanni, Abalsamo, Laura, Palucci, Ivana, Mattei, Fabrizio, Sanchez, Massimo, Giagu, Anna, Antuofermo, Elisabetta, Fadda, Giovanni, Belardelli, Filippo, Delogu, Giovanni, Gabriele, Lucia
التنسيق: Artigo
اللغة:Inglês
منشور في: Public Library of Science 2013
الموضوعات:
Research Article
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663794/
https://ncbi.nlm.nih.gov/pubmed/23717393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062751
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