Interferon Regulatory Factor 8-Deficiency Determines Massive Neutrophil Recruitment but T Cell Defect in Fast Growing Granulomas during Tuberculosis

Following Mycobacterium tuberculosis (Mtb) infection, immune cell recruitment in lungs is pivotal in establishing protective immunity through granuloma formation and neogenesis of lymphoid structures (LS). Interferon regulatory factor-8 (IRF-8) plays an important role in host defense against Mtb, al...

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Detaylı Bibliyografya
Asıl Yazarlar: Rocca, Stefano, Schiavoni, Giovanna, Sali, Michela, Anfossi, Antonio Giovanni, Abalsamo, Laura, Palucci, Ivana, Mattei, Fabrizio, Sanchez, Massimo, Giagu, Anna, Antuofermo, Elisabetta, Fadda, Giovanni, Belardelli, Filippo, Delogu, Giovanni, Gabriele, Lucia
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2013
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663794/
https://ncbi.nlm.nih.gov/pubmed/23717393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062751
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