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Role of SAP97 Protein in the Regulation of Corticotropin-releasing Factor Receptor 1 Endocytosis and Extracellular Signal-regulated Kinase 1/2 Signaling

The corticotropin-releasing factor (CRF) receptor 1 (CRFR1) is a target for the treatment of psychiatric diseases such as depression, schizophrenia, anxiety disorder, and bipolar disorder. The carboxyl-terminal tail of the CRFR1 terminates in a PDZ-binding motif that provides a potential site for th...

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Autors principals: Dunn, Henry A., Walther, Cornelia, Godin, Christina M., Hall, Randy A., Ferguson, Stephen S. G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663523/
https://ncbi.nlm.nih.gov/pubmed/23576434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.473660
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