Disruption of the Dapper3 Gene Aggravates Ureteral Obstruction-mediated Renal Fibrosis by Amplifying Wnt/β-catenin Signaling

Wnt/β-catenin signaling plays key roles in embryonic development and tissue homeostasis. Dapper3/Dact3, one of the three members of the Dapper gene family, is transcriptionally repressed in colorectal cancer and may function as a negative regulator of Wnt/β-catenin signaling. To investigate its phys...

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Main Authors: Xue, Hua, Xiao, Zhicheng, Zhang, Jing, Wen, Jun, Wang, Yuan, Chang, Zai, Zhao, Jing, Gao, Xiang, Du, Jie, Chen, Ye-Guang
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Developmental Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663521/
https://ncbi.nlm.nih.gov/pubmed/23580654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.458448
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