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Akt2 Is Involved in Loss of Epithelial Cells and Renal Fibrosis following Unilateral Ureteral Obstruction

Obstructive nephropathy is an aggressive form of chronic kidney disease (CKD), which is characterized by an epithelial-to-mesenchymal transition (EMT) and interstitial fibrosis. However, the molecular mechanisms of EMT and fibrosis are complex and not fully understood. In this study, we investigated...

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Autori principali: Lan, Aiping, Zhang, Jing, Xiao, Zhicheng, Peng, Xiaogang, Qi, Yongfen, Du, Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141797/
https://ncbi.nlm.nih.gov/pubmed/25148525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105451
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