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Akt2 Is Involved in Loss of Epithelial Cells and Renal Fibrosis following Unilateral Ureteral Obstruction

Obstructive nephropathy is an aggressive form of chronic kidney disease (CKD), which is characterized by an epithelial-to-mesenchymal transition (EMT) and interstitial fibrosis. However, the molecular mechanisms of EMT and fibrosis are complex and not fully understood. In this study, we investigated...

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Main Authors: Lan, Aiping, Zhang, Jing, Xiao, Zhicheng, Peng, Xiaogang, Qi, Yongfen, Du, Jie
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4141797/
https://ncbi.nlm.nih.gov/pubmed/25148525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105451
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