The antipsychotic-like effects of the mGlu group III orthosteric agonist, LSP1-2111, involves 5-HT(1A) signalling

RATIONALE: Several studies have suggested that modulation of the glutamatergic system via metabotropic glutamate receptors (mGlu) could be a new way to achieve antipsychotic-like activity. LSP1-2111, the group III mGlu receptor orthosteric agonist, with a high affinity towards mGlu(4) receptors, was...

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Bibliografiske detaljer
Main Authors: Wierońska, Joanna M., Acher, Francine C., Sławińska, Anna, Gruca, Piotr, Łasoń-Tyburkiewicz, Magdalena, Papp, Mariusz, Pilc, Andrzej
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2013
Fag:
Original Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3663209/
https://ncbi.nlm.nih.gov/pubmed/23474845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-013-3005-0
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