The antipsychotic-like effects of positive allosteric modulators of metabotropic glutamate mGlu(4) receptors in rodents

BACKGROUND AND PURPOSE: Because agonists at metabotropic glutamate receptors exert beneficial effects in schizophrenia, we have assessed the actions of Lu AF21934 and Lu AF32615, two chemically distinct, selective and brain-penetrant positive allosteric modulators (PAMs) of the mGlu(4) receptor, in...

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Autors principals: Sławińska, Anna, Wierońska, Joanna M, Stachowicz, Katarzyna, Marciniak, Marcin, Łasoń-Tyburkiewicz, Magdalena, Gruca, Piotr, Papp, Mariusz, Kusek, Magdalena, Tokarski, Krzysztof, Doller, Darío, Pilc, Andrzej
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2013
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753838/
https://ncbi.nlm.nih.gov/pubmed/23714045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12254
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