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The antipsychotic-like effects in rodents of the positive allosteric modulator Lu AF21934 involve 5-HT(1A) receptor signaling: mechanistic studies
RATIONALE: Diverse preclinical studies suggest the potential therapeutic utility of the modulation of the glutamatergic system in brain via metabotropic glutamate (mGlu) receptors. Lu AF21934, a positive allosteric modulator of the mGlu4 receptor, was previously shown to reverse behavioral phenotype...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Psychopharmacology (Berl) |
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| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Springer Berlin Heidelberg
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4281359/ https://ncbi.nlm.nih.gov/pubmed/25012236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-014-3657-4 |
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