Opposing efficacy of group III mGlu receptor activators, LSP1-2111 and AMN082, in animal models of positive symptoms of schizophrenia

RATIONALE: Several studies have suggested that modulation of the glutamatergic system via metabotropic glutamate receptors (mGlu) could be a new and efficient way to achieve antipsychotic-like activity. OBJECTIVES: Here, we decided to investigate the possible role of the group III mGlu receptor liga...

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Autores principales: Wierońska, Joanna M., Stachowicz, Katarzyna, Acher, Francine, Lech, Tomasz, Pilc, Andrzej
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer-Verlag 2011
Materias:
Original Investigation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3299972/
https://ncbi.nlm.nih.gov/pubmed/21952670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2502-2
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